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CASE REPORT
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A rare case of mantle cell lymphoma of nasopharynx and larynx with synchronous presentation treated with volumetric modulated arc technique radiotherapy


 Department of Radiotherapy, Batra Hospital and Medical Research Centre, New Delhi, India

Correspondence Address:
Sujata Sarkar,
Department of Radiotherapy, Batra Hospital and Medical Research Centre, New Delhi
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jrcr.jrcr_11_22

Mantle cell lymphoma (MCL) or mature peripheral B-cell lymphoid neoplasm is a type of non-Hodgkin's lymphoma. It is more common in elderly males. It is very rare, accounting for less than 1% of head and neck malignancies. MCL is usually positive for CD20, CD5, CD43, cyclin D1 and negative for CD10, CD23, and BCL6. It is a very aggressive neoplasm, and hence, patients often present in advanced stage. Due to its rare incidence and short clinical course, there are limited data on standard treatment protocols. Even with the present treatment protocols, only 30% of patients achieve complete response. Here, we present a case of synchronous presentation of MCL of the nasopharynx and larynx in a 69-year-old male. We aim to discuss the investigations and treatment done with volumetric modulated arc technique radiotherapy that led to complete response.


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    -  Sarkar S
    -  Bashir I
    -  Yotham RR
    -  Sharma R
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